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In addition to the lower incidence of nonfatal stroke in clinical trials [22, 40, 57], treatment with liraglutide or semaglutide (sc or oral) decreased the risk of dementia by 53% compared to the risk associated with placebo (HR 0.47, 95% CI 0.250.86) according to a pooled post hoc analysis of the LEADER, SUSTAIN 6 and PIONEER 6 trials, including 15,820 patients with T2DM [65]

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In fact, phytoestrogens have complex actions that may include acting as anti-inflammatory, anti-proliferative, and free radical-scavenging agents that may protect against breast cancer

The ferroptosis gene TP53 may play a critical role in diabetic foot ulcers [34], and MAPK3 may serve as a biomarker of ferroptosis, providing a novel direction for targeted therapy

(PubMed) Henkin RI, Patten BM, Re PK, Bronzert DA